Our Lab

 

Zev Gartner

Professor
Office: GH-N512E
Phone: 415-514-9962
email: Zev.Gartner@ucsf.edu




About Me

Current Position: Professor, Department of Pharmaceutical Chemistry, UCSF
Postdoctoral: UC Berkeley (mentor: Professor Carolyn Bertozzi)
Graduate: Harvard University (mentor: Professor David R Liu)
Undergraduate: UC Berkeley (mentor: Professor Yeon-Kyun Shin)
K-12: Santa Cruz, California

My Research Interests

My laboratory is working to understand how cells assemble into multicellular tissues, how the structure of tissues controls the behavior of individual cells, and how changes to tissue structure drive the progression of diseases like cancer. Toward these goals, we build, perturb, and model human tissues in vitro using techniques from the chemical, engineering, physical and biological sciences.

Katelyn Cabral

Graduate Student
Bioengineering
Office: GH-N544
Email: kcabral@berkeley.edu




About Me

I grew up in the town of Swansea, Massachusetts, where I spent my time reading, acting in plays, and dressing up in colonial outfits to teach local history. Drawn in by the ideas of creating synthetic organs in the lab, I attended Worcester Polytechnic Institute (WPI) to get my B.S. in Biomedical Engineering. As I did my first research projects on skin tissue engineering in the lab of Dr. George Pins, I quickly realized that the human body is incredibly complex, and that more biology needs to be understood in order to get synthetic organs that actually function like real ones. Undeterred, I joined the UC Berkeley/UCSF joint graduate Ph.D. program in Bioengineering. Here in the Gartner lab, I am trying to figure out the basic science of how cells form tissues, so that I can order a new liver or kidney from a catalog when I'm old.

My Research Interests

I'm interested in understanding how the processes of angiogenesis and morphogenesis are affected by the spatial, mechanical, chemical, and hemodynamic cues that endothelial cells experience.

Danny Conrad

Graduate Student
Tetrad
Office: GH-N542
Email: Danny.Conrad@ucsf.edu

About Me

California-born, -raised, and -schooled. I grew up in the Bay Area and then migrated south to spend 4 years getting my B.S. in Cell & Developmental Biology at UCSB. I got into research there by joining the Rothman Lab, where I worked on various C. elegans projects. From there I came right back to the Bay to start as a Tetrad student at UCSF, and I officially joined the Gartner Lab in 2018. When I'm not working, I'm usually hanging out with my dog Fynn (pictured right), cooking, looking for new music, grabbing a (few) beer(s) with friends, or wasting time learning useless trivia on Reddit.

My Research

In my time so far in the Gartner Lab, I've worked on both developing methods for single-cell omics and also studying how cancer genes alter tissue structure.

Olivia Creasey

Graduate Student
Bioengineering
NSF Graduate Research Fellow
Discovery Fellow
Office: GH-N542
Email: Olivia.Creasey@ucsf.edu

About Me

I’ve lived within 20 miles of the Pacific for most of my life, except for one year spent studying abroad in Spain and four years spent pursuing my undergraduate degree in Bioengineering at the University of Pittsburgh. I found my passion for tissue engineering while at Pitt through undergraduate research projects in Dr. Rocky Tuan’s lab at the University of Pittsburgh Medical Center and Adam Feinberg’s lab at Carnegie Mellon University. After graduation, I further pursued my interest in tissue engineering by working as a Research Associate at a tissue engineering biotech in San Diego for two years. While working in industry, I realized that I did not want just to make tissues but rather to know how cells make tissues. Fueled by this curiosity, I entered the Graduate Program in Bioengineering at UC Berkeley and UCSF and joined the Gartner Lab!

My Research

Inspired by my previous work in tissue engineering, I am interested in understanding how cells produce and maintain complex 3D organization within tissues, particularly in tissues containing multiple cell types. I am currently studying this process in pancreatic islets of Langerhans.

Aivy David

Lab Manager
Joint with Bo Huang
Office: GH-N546
Email: Aivy.David@ucsf.edu

About Me

B.S., Cell and Molecular Biology, San Francisco State University

Jim Garbe

Researcher
Office: GH-N544
Phone: 415-476-6251

About Me

I grew up on a farm in the corn belt west of Chicago and earned my undergraduate degree in biology at Northern Illinois University. After a short stint as a high school science teacher I returned to graduate school and received my Ph.D in biology from the Massachusetts Institute of Technology. I did post-graduate work at the University of California, Berkeley and have been a scientist at Lawrence Berkeley National Laboratory since 1994.

My Research

My research focuses on normal human mammary epithelial cells and the intrinsic and extrinsic changes that lead to immortal and malignant transformation. This has included introducing defined genetic changes into normal HMEC to create new cell lines. In the Gartner lab I will use DNA directed assembly to examine how different cell types and altered cell functions affect breast cancer related processes.

Jennifer Hu

Graduate Student
Bioengineering
NSF Graduate Research Fellow
Office: GH-N544
Email: JenniferHu@berkeley.edu

About Me

I grew up in northeast Ohio, and graduated in 2010 from Copley High School. While completing my S.B. at Harvard University, I started doing research in the labs of Debra Auguste and David Mooney. Thanks to them, as well as my lab mentors Marjan Rafat and Steve Kennedy, I decided to pursue a PhD! Now I'm a student in the UC Berkeley-UCSF Graduate Program in Bioengineering, where I joined the Gartner lab in 2015. When I have free time, I enjoy board games, baking, rock climbing, ballet, and hang gliding!

My Research

I am interested in using in vitro tissues to study how cells establish and maintain tissue structure.

Tyler Huycke

Postdoctoral Fellow
Office: GH-N542
Email: Tyler.Huycke@ucsf.edu

About Me

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My Research

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Iain Martyn

Postdoctoral Fellow
Office: GH-N542
Email: Iain.Martyn@ucsf.edu

About Me

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My Research

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Chris McGinnis

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Graduate Student
Tetrad
ARCS Scholar
Office: GH-N544
Email: Chris.Mcginnis@ucsf.edu

About Me

I grew up in the rural lakeside town of Charlotte, Vermont and lived there until moving to Connecticut for college at Wesleyan University. At Wes, I studied a mixture of sciences and humanities as a pre-med student majoring in Biology, the Science and Society Program, and Molecular Biology & Biochemistry. I also played arguably too much ultimate frisbee and drums in cinder-block-encased dorm rooms.


After graduation, I moved to Seattle for a research associate position in Lee Hood’s group at the Institute for Systems Biology. I found my love for research at ISB, where I was studying cardiomyocyte differentiation from iPSCs using single-cell qPCR. Over my two years at ISB, my research interests were honed towards the computational and theoretical analysis of cell state transitions and single-cell technology development. I moved from Seattle to the Bay Area in 2016 to join the Tetrad graduate program at UCSF, and joined the Gartner Lab in 2017, where I’ve continued research in the single-cells genomics space.

My Research

Since joining the lab, I’ve primarily focused on developing new molecular and bioinformatics tools for single-cell analysis — namely (i) an algorithm called DoubletFinder which finds doublets in scRNA-seq data and (ii) an scRNA-seq sample multiplexing technology called MULTI-seq (Multiplexing Using Lipid-Tagged Indices).

My current research projects include (i) expanding the MULTI-seq application space to new single-cell assays and (ii) using MULTI-seq to explore information processing in the immune system using fine-resolution time-course scRNA-seq experiments.

Hikaru Miyazaki

Graduate Student
Bioengineering
Joint with Ophir Klein
Office: GH-N542
Email: Hikaru.Miyazaki@ucsf.edu

About Me

I can't wait to fill in this section with lots of cool information about where I"m from!

My Research

Lots to share!

Brittany Moser

Postdoctoral Fellow
Office: GH-N542
Email: Brittany.Moser@ucsf.edu

About Me

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My Research

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Lyndsay Murrow

Damon Runyon Postdoctoral Fellow
Office: GH-N544
Email: Lyndsay.Murrow@ucsf.edu

About Me

After growing up in the Chicago suburbs, I made my way to the west coast to study chemical engineering at Stanford. Following graduation, I spent two years as a postbac at the NCI, studying potential therapeutic targets for triple-negative breast cancer. I returned to the bay area for my PhD and joined the Biomedical Sciences graduate program at UCSF. In Jay Debnath's lab, I studied mechanisms that control basal autophagy, and how a specific component of this pathway engages other intracellular trafficking pathways at the biochemical level to regulate cellular homeostasis.

My Research

Building on my previous work exploring mechanisms of cellular homeostasis, I am interested in using a bottom-up approach to interrogate mechanisms of tissue homeostasis. The goal of my research is to determine whether the physical properties that drive tissue self-organization allow stem cells to sense and respond to global tissue needs. I am using the mammary gland as a model system, computational modeling, and programmed assembly methods developed in the Gartner lab to explore how stem cell fate decisions are coordinated with the overall needs of a tissue to maintain homeostasis.

Kiet Phong

Graduate Student
Bioengineering
Office: GH-N542
Email: Kiet.Phong@ucsf.edu

About Me

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My Research

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Gabrielle Rabadam

Graduate Student
Bioengineering
Email: Gabrielle.Rabadam@ucsf.edu

About Me

Half California- and half Arizona-raised, I continued my migration eastward by moving to Boston where I got my BS in chemical engineering at Northeastern University. I got my start in research in Thomas Webster’s Nanomedicine Lab and eventually moved on to Moderna’s Rare Diseases group through Northeastern’s full-time coop program. At Moderna, I became interested in how cells’ individual transcriptional states are differentially dictated by population-level parameters. It took me all of college to realize that the scientific interests reflected in my resume were that of a quantitative systems biologist instead of a chemical engineer. I eventually gave in to this crisis of identity and moved back to California in 2019 to enter the UC Berkeley & UCSF joint PhD program in Bioengineering. I officially joined the Gartner lab in 2020, where I currently focus on developing bioinformatic tools for single-cell omics datasets.

My Research

I am interested in understanding how immune cells process structural heterogeneity as information that dictates their individual transcriptional states. To uncover this regulatory network topology, I use computational modeling, MULTI-seq experiments, and active learning approaches.

Efren Reyes

Graduate Student
Tetrad
Joint with Ophir Klein
Office: GH-N542
Email: Efren.Reyes@ucsf.edu

About Me

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My Research

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Vasudha Srivastava

Postdoctoral Fellow
Office: GH-N542
Email: Vasudha.Srivastava@ucsf.edu

About Me

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My Research

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Former Gartner Lab Members

Graduate Students


Justin Farlow - Cofounder @ Serotiny
Jennifer Liu - Scientist @ Plexxicon
Alec Cerchiari - Scientist @ Cook Medical
Noel Jee - @ Illumina Ventures
Michael Todhunter - Postdoc @ Labarge Lab (City of Hope)
Samantha Liang - Scientist @ Abbvie
Kade Southard - Postdoc @ Fletcher Lab (Berkeley)
Rob Weber - Completing MD/PhD medical training @ UCSF
Andrew Bremer - ASME Congressional Science & Engineering Fellow
Amanda Paulson - ADAM Fellow @ NIH
Jesse Zhang - Scientist @ Fluent BioSciences

Postdocs


Kyle Broaders - Assistant Professor of Chemistry @ Mount Holyoke
Chithra Krishnamurthy - Office of Technology Commercialization, UT Austin
Alex Hughes - Assistant Professor of Bioengineering @ UPenn
David Patterson - Chemistry Technology Development @ 10X Genomics

Scientists


Melanie Bocanegra - Assistant Dean @ Santa Monica College
Matthias Lachner - @ VFI
Max Coyle - Graduate Student @ King Lab (Berkeley)
Nick Selden - Medical Student @ UCSF
Alejandro Ramirez-Apodaca - @ Purigen